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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ba8f1f1acc14ba2b7b71ca906fbb0ff5fca60ccfe80dde465af245289a577d' 
  AND token = 'hg2x+PSZbthYKTXC95u+Tqwnfp+pFPb5hlht1R/EWX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}