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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab5a17dcec018ed86d5045e155296db2541afa365624678c8f5127044497790' 
  AND token = '9LdLow6Fsd0ggyv40ll4ox/SoDz9nyYWdq1rwVCxMsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}