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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb27c9feca6448075ed56dc37417219c33d77a75fc6e11b69de33983580dcec' 
  AND token = 'x+BwlnTF4dvUkyRfD5GouP85q4lxqNzkeKIp+CCumls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}