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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d18b98b844c011ea3a08aeb33a614b86b5683185f312516c19889910f279345' 
  AND token = '7OXER7NNktpvcVNrlccOOFSaLIofk3RPLN4Puw5Sero=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}