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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b3fdb5ffa5248340f27362eb091f17963ff5ec2eda2b11eb30f39091b5018e3' 
  AND token = 'e9FhwS4z8uuNeinH7nRuaBVCSeUVyQVrhVd+aH+pk1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}