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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0dc787d971d7119c844ab6f4fd43601f89ddbfd3ef54b4d4a1e6e9743ad619' 
  AND token = 'T7ywD/r2iG5/8zSIrs56aYbVLf220XXAZzVpNjqCS/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}