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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69164caee5aa4d79d215115a8c53e38a1d86e143a5ea75a86d1aa5fd912ee5fc' 
  AND token = 't6LWQAgShoNLrspvB+x38atTXoZ0PT3/lUo1S0qsNjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}