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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c1d759c73a7caf005f081d526747ca6edecb50d4cf49fc1493f663852dcd5f' 
  AND token = '78+dzyeunADk6H+cfK7fyKEXUK9gL8cq5Q+3B1V4YOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}