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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f55cd2037788520f2bf0de0da62a59b0dd8fd3f78ece4fa506b167efd959454' 
  AND token = 'iAzK+5W7N/SEYhhYyfjWSszBLf1cV+Hk4BYxFg4sSQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}