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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7c78a8fb4881223f20c0789367d5cee17b41fc186df025d80758d2258eb0df' 
  AND token = '/Q/6cmULUFjmx0WAGBMXu9Kp/AGXD014Bl4A2V3KihA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}