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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fea7d863b7129f902a2d0fda6eb220288da446f406831c7eb099633411929aaf' 
  AND token = 'ylh6eqY1ixZ/cC0lOlrhKjfmAYYdxqK5UyKH5wC4kF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}