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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa720fc0f11418f398e1a002c8d975489fac8f86bf5a2a9a5ec13c7bfd6d788' 
  AND token = 'sHZAhS229Q2h81kF9qmXN8TeEbZg/Kgmv7Iy489+sVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}