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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac245cfd3d40c43bfbef038a235a0860fdf713351af7f10226a022850b70289' 
  AND token = 'QUGcGmSZ0Ow86Z7BBMpW3IynOy/a2nPkGhRfOlmL74M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}