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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b072e259a728dbf15e5ab3ba590758d9dbfe03aa6b6ec488a399ad9c2c42bd' 
  AND token = 'ySt6Tj8+6KRSI7A9ze/9cJ1q7k4ZQQDacMntnbxmIOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}