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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c8675ed2c756bde0924f71fc27b9efb19948dc342cb31f014c6e4b9449d71ab' 
  AND token = 'PKH4JOOpsjNEAV6AFDWJc8o/gbI/QFPja6iWZ8/oC1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}