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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2381e32dad5f9e7ea28072f7a8f25f26e8e16753e1f836ef73d7aa577f66ea09' 
  AND token = 'AtvNbotQ31MbfrIRvmkpJDtpKcz5G1WzKG5JdgCtLy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}