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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f981ed906b35b060a0fc0b2b3a8975e4db2b6b0fb0aa7da30f6bd548e3120e' 
  AND token = '2Wl2tlZilqIKF3yUUZSakRieYxY3SDeupf8ep8j51IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}