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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57c796abf56a65e21a55e5ceda1c748a946fdca094f21f2604a82e842d30719' 
  AND token = 'Ho85uj7AyFO5JemMLK5KTF3apKknun4vdgQDYmto38U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}