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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0bf7601b3dee42f481f928b3e6384f8989a940711875994b126b1134843fe7' 
  AND token = 'pfxpf7gd02PFDcW1btILquIl39ymRxhJuReaGB185zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}