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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4617f6a9ee452b864b30517970a9ba9dc8cd0b3be099fac4569290e81d9a3e5' 
  AND token = 'Lw7ZLdq6saOg//mwyK8mkLR09RfKlpKNzssWA/JBCbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}