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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0994954ac173f8b1f9b0bcd800bbe09a7b3b45793dd443556204e650109b29' 
  AND token = 'QuSu391r9N4PAkLeFo/ZPUsUmGNKdF729r5AMkhq2dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}