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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52c388429c9063d2dc680b15061b19e81d62d0934ed5e2eb1867e227581918f' 
  AND token = 'YMQ+NuB2rhL7FuWcIv66CUO3gbvsIgbMjjXw6HUxZaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}