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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807ff64947b0d535a0e48a9075bbd23096d1a8a139f1c9d861cfd72b211b4721' 
  AND token = 'j8ExKzJfVbwpDMo/M9rlUfq0UYeQxc22MMDBQHiSHU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}