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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fcae0c5fb06fc75ddea5764a8c8448adb943fbe6a80377662f041b2c498e5d' 
  AND token = 'weIsyootkadHMpQRkH22LZ6OphKAKqTwYeASenXLwSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}