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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eefd8a822d4b0c87a9f152c7e678b7afe3365b85fd904d6a80bfb6485e94ffd6' 
  AND token = '1sqjS1R2F5NkRfATK+1Dl8DwUUczjHDrEEhX5UlNrA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}