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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11af57ca2ab8aa6954c4ae1d7eea61b05782963801b50d8cb82057b8f38f8760' 
  AND token = 'melRV3h3Ky9yeHsZOPSaQOHyjovVGsjRnBvcgiHhEA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}