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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5e1dc55cc26703e38a84193e2e5a34d36642119750bc26e836961ee1d3fafe' 
  AND token = 'BF+Ot3bXF9KPRaAW0KJrDBIYNI8pVHmW8UPA2ojf4SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}