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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ab43a7fb0c364bb70c580456ae13343e92ef460d288458b5cee457f272a73b1' 
  AND token = 'NvosuhJdqZpAboTdEFA1Vfx0oc1arSO4y38k5aKeVlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}