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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65510dff92a63b4fa7e149e0389624ed74d671f06c07b0b48cd1e6d15984c20' 
  AND token = 'SOJGd+/l+fVc8w+ypgXEyr3O3B20tjl2aXDdCeKmt6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}