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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8422ab7e1e211de87f5bd1371a41d0bec321823d819350142526995458661b6' 
  AND token = 'Olz8/e1Xi0PR6IaN3OFWY5LRMDsnJTpwR5JKLiGVJI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}