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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879e5284a44d317e52dc3ad3d857e4bfe5befe36d708cf069c91eb70cee77648' 
  AND token = '5Vmg/8xWE86NOLJZEXGdR7ILYH3Wg9FWfcH7D+6OCB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}