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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2125fd05da559f98e88f8b6faefdde4813fe8190c682d0070128a45d5427e32f' 
  AND token = 'UtXUwQ+/JJCJ/2QQgAJm4XQMNrDojgeJiePCSd9ix34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}