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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d5681bfde0c327f3cfbdf61552067e280cb4ba67bfd72680cf0a4e69f77d95' 
  AND token = 'B+4LN7rsJ7OXEv++lio1k0WKiO2LtZYDQMuiid3jzZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}