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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d7df2591102d280b4242ed970bd274ca35d4b49658bdb0a0a2c3f315ca5d71' 
  AND token = 'VhEp6r7kCD/kdxVY4JOHqFGuWU/R/pULIaHO3KIrnv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}