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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7f4750f3f4016726227c6c8d0223375d330cb9f92578447747ef9df4c36d28' 
  AND token = '/KyIhzB43z6E/eEY0I/qktV2tmdU5pk+7RLuWwfLNvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}