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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65298e3a47d9fa269bf24884409e0573697207d87b99166ba1495580940858e4' 
  AND token = '9IhVdgM0D5YZlcbCJldr0l6xRbxBNXi4aBF0XUjbZuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}