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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c69e9b91d9742127448f3ad08ff9d8b1da5c9baae8282c7eb2761e88981009' 
  AND token = 'kWU1IQnM2mCtT4EeAoGdzOopc+465N9oaK05pM19iLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}