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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a6e9a3aa7e42fc084282658e63b44ae383d25775144dc9b03145c89e716f06' 
  AND token = '/xlCSWbVzx7C178xM/rr/uR/pPv/CSpbCGz0swkHxwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}