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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484b9fea4913ac57d3e80a9f818f1a39ba107265ab4c9c185531d4e1d5b1facb' 
  AND token = 'wG+uBA3QfktWYphwqLtVo/FGxeif7oEXA3YFfzBO4QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}