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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8aee8a6b107f49beca936471d737e6d3b6516d788c93ae572bb0a2b2304f4c5' 
  AND token = 'sE7CPiq821Md8sJlKAMpoWHxj4B4RDfFEMw5qYtL9W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}