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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a9c0fed7ad248dec74e82ee3373b56776e91105419975f950b0089ceff9b3c' 
  AND token = '3bPj1GIS2CZR5wSWDBd3CUuXPxbi/4QvUn0dtfAeu6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}