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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '116d76c2a684f1f0090f48be78c665b1312f2b80bb8c391c40d3a74598260a40' 
  AND token = 'R+GAIt06gIHiX23Whb3mBTa6fXXKxGak8zddcsrq0pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}