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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659a86f3c4c1bcd7e894f754be7c4d194e39cad152a39a2246d15edbb1732120' 
  AND token = 'toSgHCcfGSKJ2SNU2K+VR57u8nbG1mT/+i2o4yKo/IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}