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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85286d3609e4609a401611e4f07519d7b0e69a51367c4cb0d5ca0400ee497be4' 
  AND token = 'mdgXBBqJfwx9fty0QI+SD61n4a4WhXXWetox7JJ65yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}