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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626e0a635af878b3c759268832eae8c8fa1a7ea249be64715d135c12cf0f2370' 
  AND token = 'Dno0KS8G0SZO1yDwh3kd2DuMUZiyym8xWJ2Rnz5lh58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}