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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d5121e5f78149a39a9beaa4865345550fb755718334f6c21ad985c7371a535' 
  AND token = '95C20RX5n2+FmGVA+esUkbap8Fogt1gQj1YYrgYacyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}