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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af80310b3118ede46be5eee145fb72a2a0a5011cc02ec1a24edccab80ac62c3' 
  AND token = 'PM/OICXI/gkpF6AXxGNF1jxZlqzcRI5k2luFgI+VYeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}