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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de460c805f0c941aafde4c3461c1ee45e256186d7d4b257e741f8f3fd7539c0' 
  AND token = 'IppsnsPmzgpSaD1XRcUoY2l78NHPP7pRJ9cS+/aUIpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}