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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf1c970a90cd0cb56461c68c33e50d5e6d139a9c6b0ca425ea9eb37abb5078b' 
  AND token = 'ZEs5hdWdMx6bsAji2LUnTHhyEw/UnvvLMt8WZhfJ4DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}