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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20757624a7dc06e1fdf803a6d6cf05632118cd725d8f4c54dfb7fdf6e3e392a6' 
  AND token = 'mL7NLd9WJSmoFFNf/Yz3fAs3UTaWtMDCc0lFh0M00tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}